|
KMID : 1001920140550010040
|
|
Journal of Korean Neurosurgical Society
2014 Volume.55 No. 1 p.40 ~ p.42
|
|
|
Two Cystic Cavernous Angiomas after Radiotherapy for Atypical Meningioma in Adult Woman : Case Report and Literature Review
|
|
Ruggeri Andrea Gennaro
Donnarumma Pasquale
Pichierri Angelo
Delfini Roberto
|
|
|
Abstract
|
|
|
|
A correlation between radiation therapy and cavernoma has been suspected since 1994. Since then, only a few cases of radio-induced cavernomas have been reported in the literature (85 patients). Most of them were children, and the most frequent original tumour had been medulloblastoma. The authors report a case of two cystic cavernous angiomas after radiation therapy for atypical meningioma in adult woman. This is the first case of cavernous angioma after radiotherapy for low grade meningioma. A 39-year-old, Latin american woman was operated on for a frontal atypical meningioma with intradiploic component and adjuvant radiotherapy was delivered (6000 cGy local brain irradiation, fractionated over 6 weeks). Follow-up MR imaging showed no recurrences of the tumour and no other lesions. Ten years later, at the age of 49, she consulted for progressive drug-resistant headache. MR imaging revealed two new well defined areas of different signal intensity at the surface of each frontal pole. Both lesions were surgically removed; the histopathological diagnosis was cavernous angioma. This is the first case of cavernous angioma after radiation therapy for atypical meningioma : it confirms the development of these lesions after standard radiation therapy also in patients previously affected by non-malignant tumours.
|
|
|
KEYWORD
|
|
|
Cavernoma, Cavernous angioma, Cavernoma post-radiotherapy, Radiation therapy, Cystic cavernoma
|
|
|
FullTexts / Linksout information
|
|
|
|
|
Listed journal information
|
|
   
|